Apinovex™ Polymers

Solubility-Enhancing Excipients for Amorphous Solid Dispersions.

Lubrizol’s Apinovex™ polymers are high molecular weight polyacrylic acid excipients designed to provide both processing and formulation benefits for spray-dried amorphous solid dispersions (ASDs).

Apinovex polymers enable formulators to enhance the solubility of BCS Class II and IV APIs and develop more efficient oral dosage forms with high, stable drug loading.

Oral Solid - L

Enhance Oral Solubility with Apinovex™ Polymers

  • High, stable drug loading (up to 80%) via spray drying.
  • Significantly improved drug release profile compared to crystalline APIs.
  • Enables IP protection and 505(b)(2) formulations/lifecycle management.
Discover How Apinovex™ Polymer Works
Apinovex™ Polymers Enable Solubility With Ease

Apinovex™ polymers can be easily incorporated into your drug project via spray drying or other solvent-based processes. This novel excipient has a broad API and solvent compatibility to produce Amorphous Solid Dispersions (ASD) of your brick-dust API.

Apinovex™ Polymers Enable Solubility With Ease

Apinovex™ polymers can be easily incorporated into your drug project via spray drying or other solvent-based processes. This novel excipient has a broad API and solvent compatibility to produce Amorphous Solid Dispersions (ASD) of your brick-dust API.

Apinovex™ Polymers Enable Solubility With Ease

Apinovex™ polymers can be easily incorporated into your drug project via spray drying or other solvent-based processes. This novel excipient has a broad API and solvent compatibility to produce Amorphous Solid Dispersions (ASD) of your brick-dust API.

Discover How Apinovex™ Polymer Works
Apinovex™ Polymers Enable Solubility With Ease

Apinovex™ polymers can be easily incorporated into your drug project via spray drying or other solvent-based processes. This novel excipient has a broad API and solvent compatibility to produce Amorphous Solid Dispersions (ASD) of your brick-dust API.