Carbopol® 934P NF Polymer
Carbopol® 934P NF was designed for the pharmaceutical industry in the 1960's as a high purity grade of Carbopol 934 NF polymer. Some commercially available oral formulations still contain Carbopol 934P NF polymer, but regulatory acceptance of this polymer for new formulations may be limited.
Applicable synonyms for Carbopol® 934P NF Polymer: carbomer, carboxypolymethylene
Polymerization/Residual solvent: Benzene
Key features:
- Thickener/rheology modifier
Additional features:
- Extended release agent
- Suspension and emulsion stabilizer
- Bioadhesive agent
Recommended for use in the following dosage forms:
Recommended for use in the following markets / routes of administration:
Carbopol® 934P NF polymer meets the limits cited in the current edition of the following monographs:
- United States Pharmacopeia/National Formulary (USP/NF) monograph for Carbomer 934P
- Japanese Pharmaceutical Excipients (JPE) Monograph for Carboxyvinyl Polymer
Usage levels:
- Oral solutions & suspensions: 0.2-1 wt%
- Topical: 0.5-3 wt%
Note on toxicity testing:
The toxicity of carbomers has been summarized by the Cosmetic Ingredient Review Expert Panel in their assessment of the safety of the carbomers for cosmetic ingredients. This assessment and subsequent toxicology testing have demonstrated a low toxicity and irritation potential. Lubrizol has supporting data for dermal, ocular, and oral toxicology testing for Carbopol 934P NF polymer. Bulletin 2 provides a summary of all toxicology studies for Lubrizol’s pharmaceutical grade polymers.
Additionally, Lubrizol has filed a Type V DMF with FDA. A letter of authorization (LOA) can be issued for FDA drug applications.
| Recommended Retest Date | 2 years after manufacturing date✓ |
| Recommended Storage | In airtight containers, protected from moisture and excessive temperature |